Case-Based Medicine Teaching Series Gastrointestinal Motility Disorders: Part 1 of 4

Case-Based Medicine Teaching Series
Gastrointestinal Motility Disorders: Part 1 of 4

DATE OF ORIGINAL RELEASE: May 2005
VALID FOR CME CREDIT THROUGH: May 31, 2006

NEEDS STATEMENT
Functional gastrointestinal (GI) disorders include an array of dysfunctions that occur in both the lower and the upper GI tract. These disorders—including irritable bowel syndrome (IBS), certain types of chronic constipation, nonulcer dyspepsia, and nonerosive esophageal reflux disease—have many overlapping symptoms that can often confound and confuse diagnosis. Furthermore, patients with functional GI motility disorders often have other comorbid conditions, such as fibromyalgia and psychiatric disorders, that can further complicate and delay accurate diagnosis. Recently, steps have been taken to better equip physicians with the necessary tools to properly diagnose functional GI disorders. New research has greatly enhanced our understanding of the pathophysiology of functional GI disorders, which is contributing to the development of novel and unique agents that address the multiple symptoms that often characterize these disorders.

TARGET AUDIENCE
This activity is intended for gastroenterologists and other professionals involved in the care of individuals with gastrointestinal motility disorders.

OBJECTIVES
At the conclusion of this activity, participants should be able to:

ACCREDITATION STATEMENT
Physicians: This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of CME Consultants, Inc. and McMahon Publishing Group. CME Consultants, Inc. is accredited by the ACCME to provide continuing medical education for physicians. In order to receive credit for this program, each participant must complete the evaluation form and answer sheet.

CME Consultants, Inc. designates this educational activity for a maximum of 1 Category 1 credit toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity. Any questions regarding the accreditation of this CME activity should be directed to CME Consultants, Inc.

Pharmacists: CME Consultants, Inc. has been accredited as a provider of continuing education for pharmacists by the Accreditation Council for Pharmacy Education (ACPE). In order to receive credit for this activity, all participants must complete an evaluation form and post-test certifying their completion of this activity. This activity has been accredited for 1 contact hour (0.1 CEU). There will be no fee for this activity. ACPE Universal Program Number: 309-999-05-007-H01. Initial Release Date: 5/1/05. Planned Expiration Date: 5/31/06.

Nurses: CME Consultants, Inc. is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation and designates this activity for 1.2 contact hours. In order to receive credit for this activity, all participants must complete an evaluation form and post-test certifying their completion of this activity.

ESTIMATED TIME TO COMPLETE
This activity should take approximately 60 minutes, including completion of the CME/CPE/CE post-test and evaluation form.

METHOD OF PARTICIPATION
This activity should take approximately 1 hour to complete. The participant should, in order, read the objectives and monograph, answer the 10-question, multiple-choice online post-test, and complete the online evaluation. The evaluation form provides each participant with the opportunity to comment on the quality of the instructional process, the perception of enhanced professional effectiveness, the perception of commercial bias, and his/her views on future educational needs. To receive credit for this activity, follow the post-test instructions. There is no fee associated with this activity. This credit will be valid through May 31, 2006. No credit will be given after this date.

FACULTY
Chair
Brian Lacy, PhD, MD
Associate Professor of Medicine
Department of Medicine
Division of Gastroenterology
Dartmouth—Hitchcock Medical Center
Lebanon, New Hampshire

Contributing Faculty
David Katzka, MD
Associate Professor
Gastroenterology Division
University of Pennsylvania
Philadelphia, Pennsylvania

Brian Lacy, PhD, MD
Associate Professor of Medicine
Department of Medicine
Division of Gastroenterology
Dartmouth—Hitchcock Medical Center
Lebanon, New Hampshire

Anthony Lembo, MD
Director
Motility Center
Beth Israel Deaconess Medical Center
Boston, Massachusetts

DISCLOSURE STATEMENT
CME Consultants, Inc. holds the standard that its continuing medical education programs be free of commercial bias. Now, in accordance with the disclosure policy of CME Consultants, Inc., as well as standards set forth by the ACCME, the ANCC, and the ACPE, faculty have been asked to disclose any relationship they have to companies producing pharmaceuticals, medical equipment, prostheses, etc., that might be germane to the content of their presentations and any relationship they have with the commercial supporter of the program. Such disclosure is not intended to suggest or condone bias in any presentation, but is elicited to provide readers with information that might be of potential importance to their evaluation of a given presentation. The faculty are also aware it is their responsibility to inform the readers if discussion of any non-FDA–approved uses of pharmaceuticals, medical equipment, prostheses, etc., will be included in their presentations. Faculty have reported receiving something of value from a company whose product may be germane to the content of their presentations. Something of value refers to an equity position, vested interest, receipt of royalties, consultantship, funding by a research grant, receiving honoraria for education services elsewhere, or any other relationship to a company that provides sufficient reason for disclosure, in keeping with the spirit of the stated policy.

FACULTY DISCLOSURE STATEMENT
Brian Lacy, PhD, MD, has received research support from AstraZeneca, GlaxoSmithKline, and Novartis.
David Katzka, MD, is a member of the speakers' bureau of AstraZeneca.
Anthony Lembo, MD, is a member of the speakers' bureau of Novartis, and he is a consultant for GlaxoSmithKline and Novartis.

FDA DISCLOSURE STATEMENT
The contents of some CME activities may contain discussions of nonapproved or off-label uses of some of the agents mentioned. Please consult the prescribing information for full disclosure of approved uses.
This educational activity includes discussion of published and/or investigational uses of botulinum toxin injection, isosorbide dinitrate, nifedipine, domperidone, and tegaserod.

This activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.

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